Helicobacter Pylori Diagnostics Market Global Forecast to 2026

Helicobacter is a spiral shaped gram-negative bacteria, causing chronic inflammation and infection in stomach and duodenum leading to ulceration. H. pylori is found in 50-80% of patients with gastric ulcers and in 90% of patients with duodenal ulcers. An estimated one in six individuals infected with H. pylori are expected to eventually develop peptic ulcer disease. Infected individuals experience long asymptomatic conditions with nearly 70% of individuals having minimal symptoms such as belching, bloating, nausea, vomiting, abdominal discomfort as occasional, whereas, major symptoms includes abdominal pain, peptic ulcer, bad breath etc.

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Helicobacter infection can be diagnosed by invasive that requires gastric mucosa samples, which are obtained through endoscopy and used for biopsy or non-invasive tests that requires blood or stool samples. Invasive tests include immunoassay, rapid urease test, and histology whereas non-invasive includes stool antigen assays serology tests and urea breath test.

Prevalence of helicobacter pylori is declining in developed countries, whereas its prevalence in emerging economies is increasing. For instance, according to the Faculty of Medicine of The Chinese University of Hong Kong (CUHK), 2017, around 4.4 billion people worldwide are infected with Helicobacter pylori (H. pylori). Furthermore, same source suggested that prevalence in Africa is up to 80%, which is the highest globally, while in Asia, over 50% of the population was infected with H. pylori. Moreover, according to the International Agency for Research on Cancer report 2014, in 2012, around 952,000 new gastric cancer cases occurred globally and around 734,000 gastric cancers were estimated to occur due to H. pylori infection. Such high prevalence of Helicobacter pylori in Africa and Asia is expected to fuel the regional helicobacter market growth.

The limitations associated with diagnostic tests are expected to be a major factor restraining growth of the Helicobacter pylori diagnostics market. For instance, serology-based assays have low sensitivity and specificity, as they are unable to differentiate between active infection and IgG antibodies present in case of post treatment.

Top 3 Adventure Holiday Packages In India for International Travellers

When you travel to India to enjoy the local flavour of adventure and thrill, you can explore several destinations. Every state in India has some amazing and enthralling adventure experiences. But, there are few that stand out. There are, however, some holiday packages have impeccable international standards for travel experiences. So, brace yourself for one unbelievable adventure ride in India.

Jammu and Kashmir: Crowned by the glory of India, the Himalayan range, this state is blessed with boundless natural glory. The snow-capped mountain summits, lush mountains, vast flowery meadows and pristine lakes define the Kashmir valley. The untouched beauty of this state is the perfect backdrop for high Himalayan conquests. Whether you are trekking up to Zanskar, skiing in Ladakh, water skiing in Dal Lake or white river rafting on the Lidder River stretch, you will be enamoured by the breathtaking scenery. No wonder these adventures make trip to Kashmir worthwhile.

Himachal Pradesh: It is the adventure sports capital of India. Every Himachal Pradesh tour package will include adventure sports. Most travel destinations are surrounded by adventure and fun. Rishikesh, one such site, is popular for white river rafting. Though several destinations offer paragliding, traveling to Bir in Himachal is the perfect solution to try out hand gliding and paragliding. You can also go zorbing in Khajjar. Shimla is the perfect base camp for activities like trekking and skiing in Kufri. Adventure activites in Solang valley are also refreshing and invigorating. Most tourists extend their Manali stay in their holiday packages as well. Doing this will ensure that you can enjoy trekking in Nagger, river rafting and fishing in Kullu as well as mountain biking and mountaineering around the region.

Andaman: This is an exclusive and isolated corner of India that is relatively untouched by the modern world. Nothing in the Himalayas or in a Himachal Pradesh tour package can prepare you for the fresh breath of life and spirit in Andaman. Water sports in Andaman are as essential as breathing. There are several islands in Andaman that let life and beauty flow. But, Radhanagar is perfect for romantic getaway. Snorkelling special destinations are Coby’s cove, Elephant beach, Mineva Ledge near Havelock islands and South Button. There are several specialty diving sites around the islands. You can go visit an extinct volcano near Narcondam Island or an active one near Barren Island. You could check the shipwreck near Cinque Island, Fish Rock near Passage Island, Richie’s Archipelago and marine life near Dixon’s Pinnacle. You can also enjoy island camping, fishing, and trekking. So choose your favourite sites and explore exciting Andaman.

Fixed Rate vs. Variable Rate Home Loans – Choosing the Perfect Home Loan

To Fix or Not to Fix?

If you are about to buy a house or you are about to refinance your home or investment loan you may be asking yourself, should I fix my loan or not? Everyone wants to choose the perfect home loan and so, no one wants to commit the mistake of choosing the wrong loan rate type. The question is more important especially now with interest rates being at an all time low.

To help you decide you need to know – what is the difference between a fixed rate and a variable rate home loan?

What are Fixed Rate Home Loans?

With a fixed rate home loan, you will have the assurance of knowing:

>> What your repayments will be over a set period of time

>> What your interest rate charges are over the life of the loan

>> That you have the ability to plan your finances and stick to your budget, even in times of economic uncertainty

>> That when interest rates rise, your repayments will not increase

>> That you do not have to contend with varying loan payment amounts that will fluctuate with interest rate movements

>> That you have the flexibility of locking in your fixed rate

What are Variable Rate Home Loans?

A variable rate home loan is a very popular product in the lending market and a very competitive product amongst the lenders/credit providers. A variable rate home loan allows you to:

>> Take advantage of falling interest rates when the Reserve bank decides to drop their official rates

>> Take advantage of inclusions such as, a 100% offset account, free additional repayments and redraw facilities

>> Take advantage of the equity you have built-in your home by taking a line of credit option

>> Make unlimited extra repayment each month so you can pay off your loan faster

Do You Want a Compromise between Fixed and Variable?

If you are uncertain between choosing between a fixed or variable interest home loan, you may consider a split loan. It is also known as a split rate loan. A Split Loan allows a mixture of security and flexibility, such as:

>> A portion of the repayments can be at a fixed interest rate, and

>> Another portion of the repayments can be at a variable interest rate

What will I lose by Fixing my Home Loan?

Here are the disadvantages of fixing your home loan:

>> Interest rate drops will annoy you – If interest rates go down below your fixed rate, you will be repaying more than the variable rate and you will not benefit from the rate drop

>> Can I make extra repayments? – Extra loan repayments are often not allowed if you have chosen a fixed rate, or may only be allowed with a fee. Variable rate loans usually allow you to make extra repayments at no cost

>> Break fees – Fixed rate loans may also have a break fee if you change or pay off your loan within a set period (e.g. if you sell your home)

>> No Repayment Holiday is allowed when you have a short-term financial difficulty

>> No offset account and no introductory rate are available to you

>> Cannot be used for business purposes, or building/construction loans or bridging or “off the plan” loans

Are there any Disadvantages of a Variable Rate Home Loan?

A Standard Variable Rate (SVR) home loan is one of the most popular loans available. However, you still need to make your own comparisons of the features, benefits and flexibility. Even though a variable rate loan is very popular, there are some disadvantages, such as:

>> The interest rate and repayments can rise or fall at any time

>> Changes in the interest rate are at the discretion of a lender and they are meant to be broadly in line with market condition

>> You cannot arrange a rate lock

>> You cannot pay Interest in Advance in some circumstances

How to choose theHome Loan that’s perfect for you?

It is very crucial to spend time in choosing fixed rate or variable rate. If you choose the wrong option, you will end up with an uncomfortable mortgage for a very long time. So, spend some time researching recent rate movements. If you think that the loan rate may increase in future, you can opt for fixed rate loans. And, if you believe that there are chances of further reduction in interest rates, you can select the variable rate loan.

It is also important to speak to a home finance expert who has thorough knowledge of both the fixed and variable interest rates available in the market. He/she will be able to guide you in a better way and will help you in structuring your home loan according to your needs.